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Understanding the Rationale for the HVTN 702 Trial

What have scientists learned that helped inform the design of this pivotal AIDS vaccine study in South Africa?

Published
22 August 2016
From
Vax Report
New vigour in HIV vaccine research evident at AIDS 2016

Current and forthcoming studies of vaccines to prevent HIV infection have created a new optimism that the long and challenging road to the development of such a vaccine has begun to take some promising turns. Updates on the search for preventive vaccines, presented at the 21st International AIDS Conference (AIDS 2016) in Durban, South Africa, included information on advances in the development of novel vaccines, and in the field of antibody mediated prevention (AMP).

Published
19 July 2016
From
AIDS 2016
Treatment Action Group: Pipeline Report 2016

Drugs, Diagnostics, Vaccines, Preventive Technologies, Research Toward a Cure, and Immune-Based and Gene Therapies in Development.

Published
15 July 2016
From
Treatment Action Group
HIV study confirms clinically viable vaccine paving the way for future treatments

In the study, researchers worked with a species of Old World monkeys, rhesus macaques to reproduce the trial results of RV144, the only HIV vaccine that has been tested and shown to reduce the rate of HIV acquisition in a phase III clinical trial.

Published
08 July 2016
From
Eurekalert Inf Dis
Five Exciting HIV Prevention Studies We’re Paying Attention To

What’s on the horizon of HIV prevention? Here are five clinical trials to pay attention to, if you’re interested in what the next big breakthrough in the HIV prevention field may be.

Published
30 June 2016
From
BETA blog
Improving the Effect of HIV Drugs by Use of the Tat Vaccine

A phase II clinical trial conducted in South Africa has confirmed that the therapeutic Tat vaccine against HIV/AIDS can effectively improve the response to antiretroviral drugs in people living with HIV. The results are published today in the peer-review open access Journal Retrovirology.

Published
13 June 2016
From
Istituto Superiore di Sanità press release
Men to get HPV vaccine in new drive to combat cancer, announces health minister Jane Ellison

The first men in England have started receiving the vaccination as part of a pilot to stamp out cancers and genital disease. The scheme went live in two clinics this week and will eventually see 40,000 men vaccinated to protect them against penile, anal and other cancers. The project is specifically targeted at men who have sex with men, but ministers are exploring the possibility of rolling out the HPV vaccine to all boys.

Published
08 June 2016
From
Evening Standard
New HIV-Mimicking Particles That Trigger Immune Response Could Advance AIDS Vaccine Design

Researchers with the International Aids Vaccine Initiative (IAVI) and The Scripps Research Institute (TSRI) have built tiny particles that resemble HIV on their outside and used them to provoke an immune response in animals. Their work, which was published today in the journal Cell Reports, could advance the design of an effective AIDS vaccine.

Published
23 May 2016
From
IAVI
Large-Scale HIV Vaccine Trial to Launch in South Africa

The US National Institute of Allergy and Infectious Diseases (NIAID) and its partners have decided to advance an experimental HIV vaccine regimen into a large clinical trial, the first for seven years. This new study, called HVTN 702, is designed to determine whether the vaccine is safe, tolerable and effective at preventing HIV infection among South African adults. The trial will begin in November 2016, pending regulatory approval. It will recruit 5400 HIV-uninfected men and women aged 18 to 35 years who are at risk for HIV infection.

Published
18 May 2016
From
National Institute of Allergy and Infectious Diseases
Scientists just set their sights on a new target for a HIV vaccine

he new target is part of the HIV envelope called the 'fusion peptide', and its structure is simpler than the sites that past HIV vaccine attempts have focussed on. This offers hope that, this time, we might have more luck getting the body to recognise and shut down the virus before it's too late.

Published
16 May 2016
From
ScienceAlert
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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