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Treatment guidelines news

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PEP
Postexposure Prophylaxis: Dealing With Old Guidelines

The patient responded, “With all due respect to the guidelines, in the current era when there are increasingly well-tolerated medications, why would you use a regimen that included only 2 NRTIs without a third drug in any setting where there is a risk of HIV transmission?”

Published
13 March 2013
From
Clinical Care Options (requires registration)
Prevention of mother-to-child transmission
Program to Cut HIV Transfer to Babies Gets High Marks

The African nation of Malawi is getting an A+ for its aggressive approach to preventing HIV transmission from mothers to babies.

Published
02 March 2013
From
MedPage Today HIV/AIDS
Starting treatment
When to Start ART in Africa — An Urgent Research Priority

We believe that a randomized, controlled trial should be undertaken immediately to determine when to initiate ART in Africa for maximal individual health benefit. It is feasible to conduct a large, simple trial to assess the risks and benefits of immediate ART versus deferral until a CD4+ count of 350 cells per cubic millimeter is reached.

Published
23 February 2013
From
New England Journal of Medicine
Starting treatment
Why no one is helped by dumbing down the “when to start” debate: a response to Dr Myron Cohen

This article was prompted by contributions to the “when to start” debate that avoid both it’s complexity and the lack of evidence for benefits at higher CD4 counts. This issue has broad concern for HIV positive people, doctors and health workers, and public health policy.

Published
23 February 2013
From
HIV i-Base
Treatment guidelines
Updated HIV Treatment Guidelines Include Stronger Recommendation for Acute Infection

Among the key changes are additional information about the most recently approved antiretroviral agents and a recommendation that newly infected people with HIV should be offered combination ART. The guidelines continue to recommend treatment for all people with HIV, both to reduce the risk of disease progressionand for the prevention of HIV transmission.

Published
15 February 2013
From
HIVandHepatitis.com
Treatment guidelines
Updated U.S. DHHS guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents

New recommendations on drug-resistance testing, genotypic tropism assays, starting treatment, acute infection, pregnancy and interactions.

Published
15 February 2013
From
AIDSinfo
HIV and criminal law
UK: Updated guidance on HIV transmission, the law and the work of the clinical team now published

This document is aimed at those working in HIV medicine, especially clinicians, and aims to provide information and guidance on managing issues related to sexual transmission of HIV. It applies generic ethical and professional principles but with a particular emphasis on providing a confidential environment in which sensitive matters can be discussed. The guidance sets out the roles and responsibilities of health care professionals when caring for individuals living with HIV.

Published
13 February 2013
From
HIV Justice Network
Treatment guidelines
Uganda: Health Ministry Sets New Treatment Guidelines

The health ministry has released new national clinical guidelines for the management of common conditions. It also released new essential medicines and health supplies list for HIV/AIDS, malaria, TB, pneumonia and diarrhoea in children.

Published
01 February 2013
From
AllAfrica
Sexually transmitted infections
2012 European guideline on the diagnosis and treatment of gonorrhoea in adults recommends dual antimicrobial therapy

The recommended treatment for uncomplicated Neisseria gonorrhoeae infections of the urethra, cervix, rectum and pharynx, when the antimicrobial sensitivity is unknown, is a combination of ceftriaxone 500 mg and azithromycin 2 g.

Published
22 November 2012
From
Eurosurveillance
Side-effects
Phase out D4T in poor countries

D4T used to be prescribed at 40mg but was reduced to 30mg to reduce side-effects. But even at this reduced dose many patients cannot tolerate it. So do we really need a new study to look at a lower dose (20 mg) of D4T than the current one? Many people living with HIV around the world feel that we do not and that we should plan to phase out this drug completely as has been done in Europe and the United States.

Published
07 November 2012
From
Quackdown
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