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Tshepiso study: Preventive TB therapy not associated with poor pregnancy outcomes

Initiating isoniazid preventive therapy for tuberculosis during pregnancy is not associated with a higher rate of poor maternal or infant outcomes, according to observational results from the Tshepiso study presented at CROI.

Published
12 March 2019
From
Healio
TB Preventive Therapy Safe in Pregnant Women

Pregnant women who are infected with HIV and are at risk of tuberculosis co-infection can undergo isoniazid prevention therapy without causing harm to themselves or their babies, researchers suggested here.

Published
08 March 2019
From
MedPage Today
49th Union World Conference on Lung Health: Integrating HIV treatment and TB preventative therapy greatly improves IPT adherence

When tuberculosis preventive therapy is delivered with HIV treatment services and patients get a choice in where they access treatment, completion of tuberculosis preventive therapy rises, helping to ensure people living with HIV stay healthy, researchers said here. This model of prevention should be scaled up in TB-HIV high burden settings, researchers said.

Published
05 November 2018
From
Science Speaks
49th Union World Conference on Lung Health: First promising TB vaccine candidate in 100 years needs more resources, researchers say

It's taken 100 years to see any progress in the development of a vaccine to prevent tuberculosis, a disease that kills 4,000 every day, Lucica Ditiu, executive director of the Stop TB Partnership said here. Even now, it remains uncertain that a new vaccine will see the light of day, she said, as more funding has yet to be secured for larger-scale trials to confirm the promising results of the M72 vaccine candidate.

Published
29 October 2018
From
Science Speaks
GSK candidate vaccine helps prevent active pulmonary tuberculosis in HIV negative adults in phase II study

Today, GSK and Aeras reported that GSK’s M72/AS01E[1] candidate vaccine significantly reduced the incidence of pulmonary tuberculosis disease in HIV-negative adults with latent tuberculosis infection[2] in an ongoing phase IIb clinical trial testing. These primary results published in the New England Journal of Medicine after two years of trial demonstrate an overall vaccine efficacy of 54%, with varied response rates observed in different demographic sub-groups.

Published
26 September 2018
From
Aeras
TB Treatment May Leave Some Patients Contagious

The World Health Organization’s dosage guidelines for two leading tuberculosis medications may be far too low for patients with H.I.V., allowing them to remain contagious for longer than necessary, a new study has found.

Published
09 April 2018
From
New York Times
TB vaccine trial results offer potential for BCG Revaccination, hope for subunit vaccines

Aeras, a nonprofit organization dedicated to developing vaccines against tuberculosis (TB), today announced results from an innovative clinical trial that provides encouraging new evidence that TB vaccines could prevent sustained infections in high-risk adolescents. In a prevention-of-infection Phase 2 trial conducted in South Africa, revaccination with the Bacille Calmette-Guerin (BCG) vaccine significantly reduced sustained TB infections in adolescents. An experimental vaccine candidate, H4:IC31, also reduced sustained infections, although not at statistically significant levels.

Published
19 February 2018
From
Eurekalert Medicine & Health
The 2017 Pipeline Report

Treatment Action Group (TAG) announces the launch of its annual research and development landscape analysis: The Pipeline Report: Drugs, Diagnostics, Vaccines, Preventive Technologies, Research Toward a Cure, and Immune-Based and Gene Therapies in Development.

Published
19 July 2017
From
Treatment Action Group
Person-to-person contact may cause most drug-resistant TB cases

The worst form of drug-resistant tuberculosis isn't just arising from inadequate treatment, it's mostly being spread from person to person, according to a new study of hundreds of cases in South Africa.

Published
23 January 2017
From
Reuters
Latent TB high in India's healthcare workers

While India continues to have the highest burden of tuberculosis in the world, about 23 per cent of the 8.7 million global incidences, a study reports nearly half of its healthcare workers taking care of TB patients also suffer from latent tuberculosis.

Published
17 October 2016
From
SciDevNet
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.