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Microbicides news

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Novel HIV-1 Inhibitor Shows Promise for Future Treatment of HIV in Women

Avirulins may provide a valuable chemical foundation for the development of the next generation of prophylactic medications for HIV-1 in women, according to results of a study presented at American Society of Microbiology (ASM) Microbe 2019 held from June 20-24, 2019, in San Francisco, California.

Published
26 June 2019
From
Infectious Disease Advisor
Vaginal ring can substantially impact HIV prevention, reveals mathematical model

New mathematical modelling study suggests that the dapivirine vaginal ring could substantially reduce HIV infections among South African women and be an affordable intervention depending on roll-out strategy.

Published
24 June 2019
From
Avert
REACH trial comparing vaginal ring to PrEP for HIV prevention begins

The NIH announced the start of a clinical trial that will explore the preference among adolescent girls and young women between pre-exposure prophylaxis, or PrEP, and a vaginal ring for HIV prevention.

Published
24 February 2019
From
Healio
Emerging options: Doctors and advocates discuss treatment and prevention breakthroughs on the horizon

Long-acting injectables, implantables, the dapivirine ring, vaccines, antibodies, rectal douches, and two-drug regimens.

Published
30 January 2019
From
Positively Aware
Making Clinical Trials of PrEP More Inclusive of Women, No Matter Their Pregnancy Status

Three new trials of HIV prevention drugs seek to answer directly a question that researchers inside and outside the field of HIV have explicitly avoided for years: How do drugs work -- and are they safe -- in pregnant and breastfeeding women?

Published
01 October 2018
From
The Body Pro
First Multipurpose Gel Designed to Prevent HIV, HSV, and HPV Simultaneously in Women and Men Advances in Clinical Trials

A new Phase I study of the Population Council’s multipurpose prevention technology (MPT) gel PC-1005, launching this week, will examine the safety of the gel when used rectally by both men and women. If proven effective, PC-1005 gel would be the first product to prevent three incurable sexually transmitted infections (STIs)—HIV, herpes simplex virus (HSV), and human papillomavirus (HPV)—when used either vaginally or rectally.

Published
25 June 2018
From
Population Council
Vaginal implant might stop HIV transmission

Scientists at the University of Waterloo have developed a promising new medical device that could help protect women from HIV. The technology consists of a vaginal implant that basically reduces the amount of targets the virus can latch onto during sex, and may prove a more effective measure than some anti-HIV drugs or condoms in fending off infections.

Published
17 April 2018
From
New Atlas
CROI 2018: Highlights and what’s next for advocates

Historically, CROI is heavy on basic science and early-phase research. Data from these types of studies were still prominent in 2018, but this year the meeting also broadened its lens from the lab to the ways that different strategies are, or might, have an impact in the context of people's complex lives.

Published
27 March 2018
From
AVAC
In the Era of Daily PrEP, Feds May Stop Research Funding Gels, Rings, and Douches for HIV Prevention

It's precisely because of the overwhelming success in recent years of oral PrEP that the future of the anal douche and other sorts of topically applied anti-HIV agents, such as gels and dissolvable films, all loosely termed "microbicides," is suddenly up in the air, if not outright doomed.

Published
07 March 2018
From
The Body
Genital inflammation reduces efficacy of tenofovir gel against HIV in women

The researchers performed a post hoc prospective analysis of 774 patients who participated in the Centre for the AIDS Program of Research In South Africa (CAPRISA) 004 study, a trial of topical tenofovir gel. McKinnon and colleagues measured concentrations of nine different proinflammatory cytokines from cervicovaginal lavages, and defined genital inflammation using a graduated cytokine store.

Published
28 February 2018
From
Healio
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.