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Dolutegravir preconception signal: time is up for shoddy surveillance

The news in May 2018 of a potential risk of neural tube defects in infants born to women taking dolutegravir (DTG) at the time of conception sent shockwaves through the HIV community. But, despite massive global investment, aggressive transition plans – as well as calls for years for more systematic recording of outcomes when women receive ART in pregnancy– few prospective birth registrieshave been established in other settings that can refute or confirm this finding. Meanwhile, women of child-bearing age, whether they intend to become pregnant or not, are being told that they must stick with (or go back to) efavirenz (EFV) – a drug that, before this news, was in the process of being replaced with DTG.

Published
16 July 2018
From
HIV i-Base
Dolutegravir: need to consider all pros and cons before switching in pregnancy

A young pregnant woman who switched from dolutegravir (DTG)-based ART, in response to the neural tube defect safety signal, experienced viral rebound on her new regimen. She needed to be switched back to DTG to achieve re-suppression and prevent vertical transmission.

Published
11 July 2018
From
HIV i-Base
Q&A: 'Global gag rule' hits Kenya's largest reproductive health organization

This month, Family Health Options Kenya shuttered its clinic in Kitengela, Kenya. The clinic, which had operated for more than four years, was closed in response to funding cuts due to the “global gag rule.” FHOK, which is the country’s first and largest sexual and reproductive health organization, provided 3.1 million reproductive health services in 2016.

Published
30 June 2018
From
Devex
Telling Children Their HIV Status: Interview With Dr Elizabeth Lowenthal

To learn more about the challenges associated with disclosure and how clinicians can support families throughout the process, Infectious Disease Advisor spoke with Elizabeth D. Lowenthal, MD, MSCE, assistant professor of pediatrics and epidemiology at the University of Pennsylvania Perelman School of Medicine, Philadelphia, and research director of the Global Health Research Affinity Group at Children's Hospital of Philadelphia.

Published
29 June 2018
From
Infectious Disease Advisor
How South African teenagers born HIV positive are navigating life in care

Fifteen years ago drugs were introduced that, for the first time, prevented mothers from transmitting the HIV virus to their babies. The drugs meant that children born to mothers infected with the virus could live long and fruitful lives despite being HIV positive. Since then researchers have studied the health issues facing children living with HIV and there’s a fairly good understanding about the medical challenges they face. But there’s still a lack of knowledge about the social issues these young people have to navigate.

Published
27 June 2018
From
The Conversation
Survey reveals women experience severe reproductive health issues

A new Public Health England (PHE) survey reveals that 31% of women experience severe reproductive health problems, but under half seek help.

Published
27 June 2018
From
GOV.UK
Almost half of millennial women do not get enough enjoyment from sex, Public Health England report reveals

Around 42% of 25 to 34-year-olds suffer from a "lack of sexual enjoyment", compared with less than a third of those aged from 55 to 64.

Published
27 June 2018
From
Evening Standard
Russia Cuts Back HIV Adoption Ban

A top court has scrapped Russia’s de-facto ban on allowing people who live with HIV to adopt children.

Published
25 June 2018
From
Moscow Times
New contraindication against using darunavir/cobicistat during pregnancy

On 22 June 2018, Janssen issued a Dear Doctor letter (linked below) against using darunavir/cobicistat during pregnancy. This new contraindication is based on significantly reduced plasma levels of darunavir and cobicistat during the second and third trimesters of pregnancy. Darunavir can still be used during pregnancy, but only when boosted by ritonavir.

Published
25 June 2018
From
HIV i-Base
Yes, HIV-Positive Men Can Become Fathers. Here's Two Providers Who Help Them

In HIV, we pay a lot of attention to parenthood -- but mostly from the perspective of ending mother-to-child transmission. Even then, the public health message is often mostly about the baby, not the health and well-being of the mother. But almost nowhere do we have deep discussions about reproductive options for HIV-positive men, particularly cisgender straight men.

Published
18 June 2018
From
TheBody.com

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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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