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Drug-resistant TB news

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NHS England commissions first new TB drugs in 50 years

NHS England has published a new Clinical Commissioning Policy making Janssen’s Sirturo and Otsuka’s Deltyba routinely available on the National Health Service for the treatment of pulmonary multi-drug resistant tuberculosis, offering patients easier access to the first novel therapies in nearly 50 years.

Published
25 August 2015
From
Pharma Times
Medicines Patent Pool At 5 Years: Promises Kept, Changes Ahead – An Interview With Greg Perry

The Medicines Patent Pool in Geneva is celebrating five years of existence this month. MPP Executive Director Greg Perry sat down with Intellectual Property Watch Catherine Saez to describe progress made since its inception, the success of its licensing agreement model, and plans for the future, including a possible extension to other diseases such as tuberculosis and hepatitis C.

Published
04 August 2015
From
Intellectual Property Watch
Ambitious new U.S. plan may put hundreds of thousands on MDR-TB treatment

The United States plans to place 360,000 multidrug-resistant tuberculosis patients globally on treatment over the next five years, as part of a national tuberculosis action plan currently under draft.

Published
27 July 2015
From
Science Speaks
The Medicines Patent Pool Releases Independent Feasibility Studies on Hepatitis C and Tuberculosis

As part of its ongoing consultation processes on the possibility of the Medicines Patent Pool (MPP) expanding into other disease areas, the organisation has published independent feasibility studies exploring the case for potential entry into Hepatitis C and Tuberculosis.

Published
07 July 2015
From
Medicines Patent Pool
Multidrug-resistant TB appears less transmissible in households than drug-susceptible TB

Some strains of multidrug-resistant tuberculosis (MDRTB) may have a lower fitness (be less capable of spreading) than drug-susceptible tuberculosis bacteria, according to a study published this week in PLOS Medicine.

Published
24 June 2015
From
Eurekalert Inf Dis
Large-scale study underscores value of routine Xpert testing on TB, MDR TB case finding

A study of more than 100,000 patients with suspected tuberculosis at 18 sites across India showed that routine testing using Xpert molecular technology rather than the most commonly used — and oldest — diagnostic tool of examining a sputum smear under a microscope, increased detection of TB by 39 percent and led to five times the rate of detecting resistance to a TB treatment medicine.

Published
28 May 2015
From
Science Speaks
First all-oral XDR-TB drug regimen trial launches in South Africa

The regimen is comprised of bedaquiline, which received provisional approval from the U.S. Food and Drug Administration in 2013 to treat drug-resistant tuberculosis, pretomanid a new type of antibacterial drug, and linezolid which is used off-label to treat TB.

Published
15 May 2015
From
Science Speaks
WHO moves to improve access to lifesaving medicines for hepatitis C, drug-resistant TB and cancers

WHO today published the new edition of its Model List of Essential Medicines which includes ground-breaking new treatments for hepatitis C, a variety of cancers (including breast cancer and leukaemia) and multi-drug resistant tuberculosis (TB), among others.

Published
11 May 2015
From
World Health Organization
Final fight pays off, XXDR-TB & HIV patient cured

Once an active case of extremely drug resistant (XXDR-TB) strain of tuberculosis or totally drug resistant (TDR) TB, 40-year-old Rashid Khan (name changed), has now been completely cured of his disease. Despite having total drug resistance and HIV infection, Khan got cured a few days ago. At one stage he was receiving a cocktail of 18–20 drugs between his HIV and TB regimes. But Bedaquiline made a huge difference in his treatment. He is off medicine now.

Published
24 March 2015
From
DNAIndia
MSF: More than a quarter of MDR-TB cases in Swaziland not caught by “front line of defense” in fighting the disease

The nonprofit medical humanitarian organization Médecins Sans Frontières is recommending that all patients in Swaziland who have tested positive for TB, but rapid molecular testing has found negative for drug-resistance undergo further testing, following findings that a mutation has made more than a quarter of multidrug-resistant strains undetectable by the widely used test.

Published
20 March 2015
From
Science Speaks
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