Search through all our worldwide HIV and AIDS news and features, using the topics below to filter your results by subjects including HIV treatment, transmission and prevention, and hepatitis and TB co-infections.

Drug interactions and pharmacokinetics news

Show

From To
Closer Monitoring Recommended for Older Patients Treated With Dolutegravir for HIV

The maximum concentration of the integrase inhibitor dolutegravir (DTG) was significantly higher in people living with HIV who are more than 60 years old compared with younger individuals, according to new findings published in Clinical Infectious Diseases.There have been recent concerns about DTG-related neuropsychiatric toxicity, especially among older patients with HIV.

Published
11 June 2018
From
Infectious Disease Advisor
FDA says Prezcobix should not be given to pregnant women

Darunavir/cobicistat — marketed as Prezcobix (Janssen) in the United States — should not be given to pregnant women with HIV because of substantially lower exposures of the two medications during pregnancy, the FDA said. The agency updated the label for the once-daily, fixed-dose tablet to reflect the change, which it said was based on data from a small clinical trial involving pregnant women.

Published
11 June 2018
From
Healio (requires free registration)
Closer Monitoring Recommended for Older Patients Treated With Dolutegravir for HIV

The maximum concentration of the integrase inhibitor dolutegravir (DTG) was significantly higher in people living with HIV who are more than 60 years old compared with younger individuals, according to new findings published in Clinical Infectious Diseases.

Published
11 June 2018
From
Infectious Disease Advisor
Differing drug distribution in penis and rectum of men taking TDF/FTC PrEP

Men using tenofovir/emtricitabine (TDF/FTC) for preexposure prophylaxis (PrEP) had detectable drug levels in the urethra more often than on the glans penis, according to results of an 18-man study. FTC concentrations proved similar on urethral and rectal swabs, but tenofovir (TFV) levels were lower on urethral specimens than on rectal swabs.

Published
25 May 2018
From
NATAP
How Well Do Docs Manage Potential Conflicts Between Hep C and HIV Meds?

A recent study of Dutch clinicians found that they generally did a good job of preventing drug-drug interactions.

Published
10 April 2018
From
Poz
Dolutegravir and Rifapentine study stopped due to serious toxicities

A study examining pharmacokinetic interactions between the first-line HIV drug dolutegravir and a once-weekly tuberculosis regimen was terminated early after NIH researchers found that the combined use of the treatments led to “unexpected and serious toxicities” in healthy participants.

Published
01 March 2018
From
Medical Brief
Taking multiple Rx drugs raises risks for aging adults with and without HIV

Taking five or more prescription medications increases the risk of hospitalization and death in older adults infected with HIV and comparable adults without HIV. The findings of this Yale-led study highlight the potential risks of prescribing additional drugs to patients with multiple medical conditions.

Published
01 February 2018
From
Yale News
Drug interaction concerns may negatively affect HIV treatment adherence among transgender women

Participants in NIH-supported study apprehensive about combining HIV medications and hormones.

Published
25 July 2017
From
NIAID
Taking Birth Control With HIV Treatment or PrEP Is Largely OK

Women taking various forms of hormonal contraceptives can likely combine them safely with antiretrovirals (ARVs), whether as HIV treatment or in the form of Truvada (tenofovir disoproxil fumarate/emtricitabine) as pre-exposure prophylaxis (PrEP) against the virus. The one ARV that may be problematic to combine with such forms of birth control is Sustiva (efavirenz), which is included in Atripla (efavirenz/tenofovir disoproxil fumarate/emtricitabine).

Published
30 May 2017
From
Poz
Unexpected side effects with generic abacavir – and potential for rare reactions to other generic ARVs

Several anecdotal reports of mouth ulcers have recently been reported in people switching to generic abacavir in the UK. This should highlight awareness of the potential of likely-rare new side effects, even when both formulations have been approved as bioequivalent.

Published
23 May 2017
From
HIV i-Base
← First12345...8Next →
Tell us why you visited aidsmap today
minimise

Could you help us by answering three questions on why you’ve visited aidsmap today?

You can close this questionnaire and come back to it later. Just click on the pink circle.

What prompted you to visit aidsmap today?

What exactly are you looking for? What specific questions do you need answered?

Have you found what you were looking for?

close

Thank you for your feedback

Thank you very much for taking time to fill in this questionnaire. NAM really values your feedback. It helps make the information we provide better.

If you have any other comments on the content of this website, we would be interested to hear from you. Please email info@nam.org.uk.

Filter by country

Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
close

This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.