Clinical trials: latest news

Clinical trials resources

  • Clinical trials

    This factsheet provides a brief introduction to the types of clinical trial that people with HIV might be asked to join. There is also information on how...

    From: Factsheets

    Information level Level 2
  • Thinking about joining a clinical trial?

    People decide to take part in clinical trials for different reasons. It is something that is best decided in close consultation with your healthcare team. Generally, it...

    From: Factsheets

    Information level Level 2

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  • Psychologists Welcome Analysis Casting Doubt on Their Work

    The field of psychology sustained a damaging blow Thursday: A new analysis found that only 36 percent of findings from almost 100 studies in the top three psychology journals held up when the original experiments were rigorously redone.

    01 September 2015 | New York Times
  • Scientists have the tools to end the HIV epidemic; they just need better ways to use them

    In the past, there was a sense that stopping the HIV/AIDS epidemic would require some radically new biomedical intervention, such as a cure or a vaccine. The growing consensus, however, is that the tools needed to stamp out HIV already exist if they could just be used in the right way.

    08 July 2015 | Nature
  • Leading Canadian researcher calls for inclusion of co-infected people in large HCV clinical trials

    Stephen Shafran from the University of Alberta performed a major review of clinical trials of many DAA-containing HCV therapies used for the treatment of HCV mono-infection as well as HIV-HCV co-infection. Cure rates of HCV are “remarkably similar” in HCV mono-infected and co-infected participants who were treated with the same regimen and who have the same strain (genotype) of HCV.

    07 July 2015 | CATIE
  • Risks vs rewards: why people with HIV volunteer for 'cure' research

    A recent survey of people living with HIV in the United Kingdom found that more than half would participate in a clinical study to develop a cure for HIV, despite this posing a risk to their health. Why would someone choose to do this?

    24 June 2015 | The Conversation
  • START Making Sense

    The story of the START trial will continue to be told for a long time to come. For some it will be a tale of rigorous perseverance in the face of strong counter-prevailing headwinds and ultimate arrival at a result that is solid and conclusive. Others will see a single-minded and aggressive defense of a trial by investigators who refused to accept not only the obvious but also the evidence that rendered their design obsolete and even unethical.

    19 June 2015 | North Carolina AIDS Training and Education Center
  • Evidence-based policy movement "unhelpful and unscientific"

    Dr Flora Cornish, Associate Professor in Qualitative Research Methodology at the London School of Economics, on why the aspirations of the evidence-based policy movement for bottom line answers are unscientific and unhelpful when evaluating the efficacy of community mobilisation in tackling HIV.

    01 June 2015 | International HIV/AIDS Alliance
  • i-Base Q&A on the START study results

    On 27 May 2015, early results showed that the early treatment group did better. One of the surprises is that even at very high CD4 counts, treatment reduces the risk of HIV related illnesses.

    28 May 2015 | HIV i-Base
  • WHO Advances Research and Development Financing Effort; Global R&D Observatory To Launch In January

    World Health Organization members in committee this week took note of a report by the Consultative Expert Working Group on Research and Development: Financing and Coordination (CEWG), which was set up to find ways to fund research on diseases afflicting poor populations which have little market incentive for the private sector. The report included a proposal for a voluntary pooled fund that would focus on the development of effective and affordable health technologies for such neglected diseases.

    26 May 2015 | Intellectual Property Watch
  • Africa's health centre at the frontline of HIV research

    The Africa Centre for Health and Population Studies sits in the HIV capital of the world. The sleek modern building, rising out of an otherwise rustic setting near Mtubatuba in South Africa, attracts world-class researchers looking to wage war against the resilient virus.

    26 May 2015 | The Guardian
  • Tense debate over ethics of trial on link between HIV, contraception

    Thus far, most evidence pertaining to the use of Depo-Provera and the risk of HIV-infection come from observational studies, which can reveal whether two factors are associated with each other, but cannot determine whether one is causing the other to occur. Given this limitation, some scholars are looking to develop a randomised controlled trial, an experimental study that is better at determining cause and effect.

    01 May 2015 | Mail & Guardian
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