Cardiovascular disease

Cardiovascular disease features

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  HIV and TB in Practice for nurses: non-communicable diseases, HIV and TB

  Conditions such as cancer, heart disease and diabetes in low- and middle-income countries, and awareness of these conditions in people living with HIV and/or TB. ...

  From:  HIV & AIDS treatment in practice

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  HIV drugs and heart attacks: what’s the real story?

  The ‘Data Collection on Adverse Events of Anti-HIV Drugs’ study (a large study known as D:A:D, which is monitoring the effects of HIV drugs) continues to find...

  From:  HIV treatment update

Cardiovascular disease in your own words

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  Life on HIV treatment – a personal perspective

  I’ve been taking HIV treatment for ten years – that's longer than the average life expectancy of someone with HIV when I was diagnosed back in 1991. I’ve...

  From: In your own words

Cardiovascular disease news from aidsmap

• Genetics make a large contribution to cardiovascular risk for people with HIV

  Genetic background has a major impact on the risk of coronary artery disease for people with HIV, results of a large study published in the online edition of Clinical Infectious Diseases show. An unfavourable genetic background increased the risk of ...

  24 April 2013 | Michael Carter

• Almost three-quarters of people starting HIV therapy in Tanzania have dyslipidemia after three years of treatment

  Approximately 75% of HIV-positive patients in Tanzania had lipid abnormalities three years after starting antiretroviral therapy, research published in the online edition of Clinical Infectious Diseases shows. The study involved 6385 people starting first-line HIV therapy in Dar ...

  28 March 2013 | Michael Carter

• HIV increases the risk of heart attack, even in people with a suppressed viral load

  Infection with HIV is associated with an increased risk of heart attack, investigators from the United States report in the Journal of the American Medical Association Internal Medicine. Importantly, this finding was based upon comparison of HIV-positive and HIV-negative individuals ...

  19 March 2013 | Michael Carter

• Management of hypertension reduces the risk of cardiovascular disease for HIV-positive people with high blood pressure

  New Swiss research has shown the benefits of treating hypertension in HIV-positive people. The investigators calculated that the reduction in blood pressure achieved by their patients would “significantly reduce cardiovascular endpoints”. Traditional, rather than HIV-associated, risk factors were associated with increases ...

  21 January 2013 | Michael Carter

• Poor CD4 response to HIV treatment increases risk of death from non-AIDS-related illnesses, even for those with higher baseline counts

  A poor increase in CD4 cell count after starting antiretroviral therapy is associated with an increased risk of death due to non-AIDS-related causes, Danish investigators report in the online edition of AIDS. All the participants in the study had a ...

  28 December 2012 | Michael Carter

• Traditional risk factors strongest predictors of sub-clinical cardiovascular disease in people about to start HIV therapy

  Sub-clinical cardiovascular disease in people with HIV is more strongly associated with traditional risk factors for heart disease rather than inflammation or HIV-related parameters, US research published in the online edition of AIDS suggests. The cross-sectional study involved ...

  17 December 2012 | Michael Carter

• Smoking the biggest single risk factor for acute heart disease in people with HIV

  Smoking is the single biggest risk factor for acute coronary syndrome in HIV-positive adults, Spanish researchers report in the online edition of HIV Medicine. Smoking was a much more important factor than diabetes and hypertension combined. “Future efforts to ...

  19 November 2012 | Michael Carter

• Traditional risk factors predict neurocognitive impairment in people with HIV

  Neurocognitive impairment in people with HIV – loss of memory, poor concentration and declining mental ability – is most likely to be happening for the same reasons as in the wider population, and the risk of ...

  31 October 2012 | Michael Carter

• Obesity is a risk factor for co-occuring chronic health problems in patients with HIV

  Obesity is associated with the clustering of multiple health problems in HIV-positive people, investigators from the US report in the online edition of the Journal of Acquired Immune Deficiency Syndromes. Compared to people of a healthy weight, obese individuals were ...

  10 October 2012 | Michael Carter

• Starting HIV treatment reduces the risk of serious non-AIDS-related diseases

  Serious non-AIDS-defining illnesses are common in people recently diagnosed with HIV, Spanish investigators report in the online edition of AIDS. “Clinicians should be aware that during the initial follow-up after HIV diagnosis NAE [non-AIDS events] do occur,” comment the authors. ...

  09 October 2012 | Michael Carter

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Cardiovascular disease news selected from other sources

• Maternal abacavir, smoking tied to heart markers in HIV-exposed kids

  HIV-exposed but uninfected (HEU) children of HIV-positive mothers who took abacavir, smoked, or drank alcohol had elevated levels of cardiac biomarkers that could signal heart trouble, according to analysis of the US Pediatric HIVAIDS Cohort Study (PHACS). The study also linked cardiac biomarkers to some echocardiographic abnormalities.

  07 May 2013 | International AIDS Society

• Protein Structure Discovery Could Lead to Better Treatments for HIV, Early Aging

  Researchers at the University of Virginia School of Medicine have determined the molecular structure of a protein whose mutations have been linked to several early aging diseases, and to side effects of common HIV and AIDS medications.

  11 April 2013 | University of Virginia press release

• HIV Infection Severity Linked to Atrial Fibrillation

  More advanced HIV may independently boost the chances of atrial fibrillation (Afib), a VA registry study showed.

  04 April 2013 | MedPage Today

• Recreational cocaine use linked to conditions that cause heart attack

  Recreational cocaine users may have higher blood pressure, stiffer arteries and thicker heart muscle walls than non-users -- all of which can cause a heart attack. The Australian study is the first to document some of these cardiovascular abnormalities in seemingly healthy cocaine users long after the immediate effects of cocaine have worn off.

  13 March 2013 | Science Daily

• Every year of statin therapy boosts diabetes risk 10% in US HIV cohort

  Every year of treatment with lipid-lowering statins boosted the risk of diabetes 10% in members of the HIV Outpatient Study (HOPS). The results confirm an earlier finding of self-reported diabetes associated with statin use in a large general-population study of US postmenopausal women, but the impact of statins seemed more modest in the HOPS analysis.

  07 March 2013 | EATG / NATAP

• HIV linked to higher chance of heart attack

  People with HIV are almost 50 percent more likely to have a heart attack than those who aren't infected with the virus - even after taking into account their other health risks, according to a new study.

  06 March 2013 | Reuters

• HIV Drugs Ease Inflammation in 'Controllers'

  Putting HIV controllers -- who ordinarily don't need therapy -- on highly active antiretroviral treatment (HAART) appeared to reduce markers of chronic inflammation, a researcher said here.

  04 March 2013 | MedPage Today HIV/AIDS

• Drug interaction warning for hepatitis C: serious side effects when using telaprevir and bosentan

  A medical team in Paris, France, has reported an unexpected and disturbing drug interaction between a drug used to treat pulmonary arterial hypertension—bosentan (Tracleer)—and the HCV drug telaprevir. The interaction led to serious side effects.

  15 February 2013 | CATIE

• Copy of Drug interaction warning for hepatitis C: serious side effects when using telaprevir and bosentan

  A medical team in Paris, France, has reported an unexpected and disturbing drug interaction between a drug used to treat pulmonary arterial hypertension—bosentan (Tracleer)—and the HCV drug telaprevir. The interaction led to serious side effects.

  15 February 2013 | CATIE

• HIV11: Lipid Levels Are Higher among HIV+ People on ART, Immune Suppression May Play a Role

  People with HIV on suppressive antiretroviral therapy (ART) have "considerably higher" blood lipid levels relative to untreated individuals or those on less effective treatment, researchers reported at the 11th International Congress on Drug Therapy in HIV Infection (HIV11) last month in Glasgow. They also found that greater immune deficiency, as indicated by lowest-ever CD4 count, was associated with lipid elevations.

  17 December 2012 | HIVandhepatitis.com

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