In Amsterdam, researchers have established a large cohort, called AGEhIV, of both HIV-positive and HIV-negative people of similar age and risk behaviours. Young MSM in this study, regardless of HIV infection, were surprisingly at risk for having thinner-than-normal bones.
01 October 2014 | CATIE
Gilead is running nine phase III studies involving tenofovir alafenamide (TAF), which reflects the importance of the drug to Gilead's future HIV business. It is collecting an enormous amount of clinical data in which to make the case that TAF should be a preferred backbone drug for new and existing HIV patients, as well as patients who cannot use Viread because of pre-existing kidney conditions.
23 September 2014 | The Street
People living with HIV are at greater risk of geriatric syndromes such as frailty and difficulty with daily activities than HIV negative people of the same age -- and this can have a significant effect upon their quality of life as they age, according to several studies presented at the 14th Conference on Retroviruses and Opportunistic Infections (CROI 2014) last month in Boston.
08 April 2014 | HIVandHepatitis.com
In a cohort study, babies of mothers taking tenofovir (Viread) had an average whole-body bone mineral content about 8 grams less than babies whose mothers did not use the drug, according to George Siberry, MD, of the National Institute of Child Health and Human Development in Bethesda, Md
07 March 2014 | MedPage Today
The HIV Medicine Association of the Infectious Diseases Society of America has updated its HIV care guidelines to reflect the fact that people with HIV are now living normal life spans, and their physicians need to focus on preventive care, including screening for high cholesterol, diabetes and osteoporosis.
14 November 2013 | Eurekalert Inf Dis
A switch from tenofovir/emtricitabine (TDF/FTC) to abacavir/lamivudine (ABC/3TC), both with atazanavir/ritonavir, maintained viral suppression through 48 weeks in a noninferiority analysis and improved bone and kidney markers. Four people in the ABC/3TC arm (2%) and one in the TDF/FTC arm (1%) had study-defined virologic failure by week 48.
19 September 2013 | NATAP
Continued bone loss among HIV positive men with osteopenia was modest overall, but about 25% of those taking tenofovir (Viread, also in 4 antiretroviral coformulations) experienced significant loss, according to a recent study. A related meta-analysis found that HIV infection is associated with a modest likelihood of new fractures, with smoking and hepatitis C virus (HCV) coinfection further increasing the risk.
07 June 2013 | HIVandHepatitis.com
Bone mineral density was below the general population norm in US children perinatally infected with HIV and lower than in children perinatally exposed to HIV but uninfected.
21 January 2013 | International AIDS Society
People who stopped antiretroviral therapy in the SMART trial had less bone loss and lower levels of bone metabolism biomarkers than people who remained on continuous antiretroviral therapy (ART), according to a report in the January 8, 2013, advance edition of Journal of Bone Mineral Research.
16 January 2013 | HIVandHepatitis.com
Old age comes faster and hits harder for those infected with HIV, a fact aging health activist Ron Swanda knows all too well.
30 November 2012 | AFP